What is Pregnenolone?
Pregnenolone is used as a natual hormone replacement therapy. It is a steroid hormone and a precursor, or building block, for all other steroid hormones in the body. Made from cholesterol, it is produced naturally in the adrenal glands and in small amounts by many other organs and tissues including the brain, skin, liver, and retina.
Pregnenolone’s role in human biology is key as it is converted directly into DHEA which then converts to both testosterone and estrogens. Pregnenolone also converts directly into progesterone which upon conversion produces estrogens, cortisol, and aldosterone – hormones necessary for basic metabolic processes throughout the body.
Early studies of pregnenolone showed its benefits to be an energizing, anti-stress agent for the body. When given to factory workers and pilots, they reported less fatigue as well as an enhanced sense of happiness and well-being.
Further studies corroborated these early findings and showed additional benefits of memory enhancement, mental clarity, and mood elevation.
Pregnenolone modulates two key nerve receptors in the brain, the NMDA receptors and the GABA receptors. It enhances NMDA receptor function which is involved in alertness, memory, and learning functions.
It also inhibits GABA receptors responsible for relaxation, mental slowing, sedation, and sleep. Therefore too little NMDA response combined with too much GABA action promotes mental sluggishness and depression. Conversely, by raising NMDA activity and lowering excessive GABA activity, pregnenolone acts as a natural antidepressant.
Pregnenolone Benefits and Uses
» Can improve well-being and support a healthy mood
» Pregnenolone helps those suffering from depression
» Can improve memory function and mental alertness
» Hormone support for both men and women
» May promote healthy energy levels
» Used for female perimenopause, menopause (including hot flashes) and thyroid hormone replacement therapy
» Assists female hormone imbalance in the menstrual cycle
Pregnenolone Dosage
Take 1 capsule daily.
Cautions Using Pregnenolone
• Pregnant or lactating women should consult a health practitioner before using this product.
• Prolonged use of this product may cause higher than normal levels of androgens and estrogens in the body which theoretically may increase the risk of prostate, breast, ovarian, and other hormone-related cancers.
• It is not recommended to use this product for continued use without supervision by your professional healthcare provider.
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Supplement Facts Serving Size: 1 capsule |
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Amount per serving |
Amount |
% Daily Value |
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Pregnenolone |
50 mg |
* |
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* daily value not established
Other ingredients: Rice flour, magnesium stearate, silicon dioxide.
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This product is not intended to diagnose, treat, cure or prevent any disease. The Food and Drug Administration have not evaluated these statements. The statements above are the views of the manufacturer and are intended for reference only. The manufacturer can sometimes unexpectedly improve their formulation so be sure to check the product labelling, before consumption, for the most up to date information.
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